Proluton Depot 500 mg Injection

Proluton Depot 500 mg Injection – Product Description

Brand Name: Proluton Depot
Active Ingredient: Hydroxyprogesterone caproate
Formulation: Injection
Manufacturer: Bayer schering pharma.
Pack Size: Typically available in vials (1 ml or 2 ml) containing 500 mg of hydroxyprogesterone caproate

Description:

Proluton Depot 500 mg is a long-acting injectable form of hydroxyprogesterone caproate, a synthetic progestogen (progesterone-like hormone). This medication is used in managing various reproductive health issues, including supporting pregnancies at risk for preterm birth. Hydroxyprogesterone caproate works by mimicking natural progesterone, a hormone crucial in maintaining pregnancy and regulating the menstrual cycle.

Indications:

• Prevention of Preterm Birth: Proluton Depot 500 mg is primarily used in women with a history of preterm birth, aiming to reduce the risk of preterm delivery in subsequent pregnancies.

• Hormonal Imbalance: It is used to treat conditions associated with hormonal imbalances, including irregular menstrual cycles and certain forms of infertility.

• Endometrial Hyperplasia: Used for preventing and treating endometrial hyperplasia, a condition characterized by thickening of the uterine lining.

• Amenorrhea: It is effective in managing amenorrhea (absence of menstruation) due to insufficient progesterone production.

• Hormonal Replacement Therapy: Proluton Depot may be used as part of hormone replacement therapy (HRT) in postmenopausal women or women with hormonal deficiencies.

  Dosage and Administration:

• For Prevention of Preterm Birth:
  The usual recommended dose is 500 mg, administered as an intramuscular injection, once a week, starting at 16–20 weeks of pregnancy and continuing until 37 weeks of gestation or delivery, whichever comes first.

• For Menstrual Disorders or Amenorrhea:
  The typical dose for managing menstrual disorders or amenorrhea is 500 mg administered once every 4–6 weeks, depending on the doctor’s recommendation.

• For Hormonal Imbalance:
  500 mg may be administered as part of hormone therapy, either for endometrial conditions or during certain fertility treatments.

  Side Effects:

Common side effects of Proluton Depot 500 mg Injection include:

• Injection site reactions, such as pain, redness, or swelling.

• Headache or mood swings.

• Fatigue, dizziness, or nausea.

• Weight gain, bloating, or fluid retention.

• Breast tenderness.

Less common but serious side effects may include:

• Severe allergic reactions (swelling, itching, rash, or difficulty breathing).

• Signs of blood clots, such as sudden chest pain, shortness of breath, or swelling of the legs.

• Vision problems or sudden, severe headache (possible signs of a stroke).

• Yellowing of the skin or eyes, which could indicate liver problems.

• Unusual vaginal bleeding.

If any serious side effects occur, contact a healthcare provider immediately.

Precautions and Warnings:

• Pregnancy: Proluton Depot is used during pregnancy to prevent preterm birth but should only be used under medical supervision.

• Breastfeeding: This medication can pass into breast milk; consult with a healthcare provider if breastfeeding.

• Liver Disease: Hydroxyprogesterone may affect liver function, so it should be used with caution in people with liver disorders.

• Blood Clotting Disorders: People with a history of blood clots, deep vein thrombosis (DVT), or pulmonary embolism should use Proluton Depot with caution.

• Cancer History: Women with a history of hormone-sensitive cancers (such as breast cancer) should inform their healthcare provider before using Proluton Depot.

• Diabetes: Proluton Depot may influence blood sugar levels, so individuals with diabetes should monitor their levels closely while using this medication.

Storage Instructions:

• Store the injection at room temperature (15°C to 30°C).

• Do not freeze the injection.

• Keep the vial in its original packaging to protect it from light.

• Keep out of reach of children.

  Disclaimer:

The dosage and administration of Proluton Depot 500 mg should always be prescribed by a qualified healthcare provider. Regular monitoring may be required to assess its effectiveness and manage any potential side effects. Always follow the prescribed instructions and consult your doctor if you experience any unusual symptoms or side effects.