Zidovir 100mg (Zidovudine)

Zidovir 100 mg – Product Description

Brand Name: Zidovir 100
Manufacturer: Cipla Ltd.
Drug Class: Antiretroviral (Nucleoside Reverse Transcriptase Inhibitor – NRTI)
Route of Administration: Oral
Packaging: Bottle of 100 capsules (may vary by manufacturer)

Product Description & Uses

Zidovir 100 mg contains Zidovudine, an antiretroviral drug used in the treatment and prevention of HIV/AIDS. It works by inhibiting the replication of the human immunodeficiency virus (HIV), helping to control the infection and improve immune function.

🔹 Indications:
✅ HIV Infection – Used as part of combination antiretroviral therapy (ART)
✅ Prevention of Mother-to-Child Transmission (PMTCT) – Given to pregnant women and newborns to prevent HIV transmission
✅ Post-Exposure Prophylaxis (PEP) – Used to reduce the risk of HIV infection after exposure

Dosage & Administration

• For Adults & Adolescents (≥30 kg): 300 mg daily (divided into 100 mg every 8 hours or 200 mg every 12 hours)

• For Children (Based on weight): Dosage varies depending on body weight and doctor’s recommendation

• Take with or without food

• Must be used in combination with other antiretroviral drugs

Side Effects & Precautions

⚠ Common Side Effects:
🔹 Headache, Nausea, Vomiting
🔹 Fatigue, Muscle Pain
🔹 Loss of Appetite
🔹 Anemia (Low Red Blood Cell Count)

⚠ Precautions:
🚫 May cause bone marrow suppression – Regular blood tests required
🚫 Risk of lactic acidosis & liver toxicity – Watch for severe weakness, stomach pain, or jaundice
🚫 Use with caution in kidney/liver disease patients
🚫 Not a cure for HIV/AIDS – Requires lifelong therapy

⚠ Drug Interactions:
❌ Avoid combining with Stavudine (d4T) (antagonistic effect)
❌ Use cautiously with other bone marrow-suppressing drugs (e.g., chemotherapy, ribavirin)

Storage & Packaging

📦 Zidovir 100 mg comes in:

• Bottle of 100 capsules (varies by manufacturer)

• Store at room temperature (15-30°C), away from moisture and direct sunlight

  Disclaimer

• Zidovir 100 mg should only be used under medical supervision as part of an HIV treatment plan.

• Regular blood tests are required to monitor for anemia and liver function.

• Stopping treatment abruptly can lead to viral resistance.

• If severe side effects like difficulty breathing, muscle weakness, or pale skin occur, seek immediate medical attention.