Danogen 50 mg Capsule

Danogen 50 mg Capsule – Product Description

Brand Name: Danogen
Active Ingredient: Danazol
Formulation: Capsule
Manufacturer: Cipla Ltd.
Packaging: strips of 10 dispersible tablets per pack.

Description:

Danogen 50 mg Capsule contains Danazol, a synthetic steroid that belongs to a class of medications known as androgens. Danazol works by inhibiting the production of certain hormones that affect the reproductive system, specifically the production of estrogen and progesterone. This action helps in treating conditions related to hormonal imbalance, such as endometriosis, fibrocystic breast disease, and hereditary angioedema.

Danogen is often used to treat conditions where excess estrogen is contributing to symptoms, and its action helps to reduce symptoms such as pain and swelling by lowering the levels of estrogen in the body.

Indications:

Danogen 50 mg Capsule is prescribed for the following conditions:

• Endometriosis: Danogen is used to manage symptoms associated with endometriosis by suppressing ovarian estrogen production. It helps reduce pelvic pain and other symptoms associated with this condition.

• Fibrocystic Breast Disease: It is used to treat symptoms such as breast tenderness, swelling, and pain caused by fibrocystic breast changes, where lumps or cysts form in the breast tissue.

• Hereditary Angioedema: Danogen is sometimes used to prevent or reduce the frequency of attacks of angioedema (swelling) in individuals with hereditary angioedema.

• Other hormonal imbalances: It may also be used off-label to treat certain other hormonal imbalances as determined by a healthcare provider.

Dosage and Administration:

• Endometriosis:

  • The usual dose is 100 mg to 200 mg daily, which can be adjusted based on the individual’s response and tolerability. Treatment typically continues for 6 to 9 months, after which your doctor may reassess the need for further treatment.

• Fibrocystic Breast Disease:

  • The usual dose for fibrocystic breast disease is 50 mg to 200 mg daily. Treatment duration can vary and may be continued for up to 3 to 6 months.

• Hereditary Angioedema:

  • Danogen 50 mg is typically prescribed for 10 to 14 days to control acute episodes of hereditary angioedema. The dosage may vary depending on the severity of the condition and patient response.

Your healthcare provider will adjust the dose based on your specific needs and response to the treatment. Always follow the prescribed dosage and schedule provided by your healthcare professional.

Side Effects:

Danogen may cause some side effects, and while not everyone experiences them, the common and serious side effects include:

Common Side Effects:

• Weight gain

• Acne

• Voice deepening or hoarseness

• Increased body or facial hair (hirsutism)

• Hot flashes

• Mood changes (e.g., depression, irritability)

• Reduced breast size

• Nausea or vomiting

Serious Side Effects:

• Liver dysfunction: Symptoms may include yellowing of the skin or eyes, dark urine, or abdominal pain.

• Blood clotting problems: Danogen can increase the risk of blood clots, leading to conditions such as deep vein thrombosis (DVT) or pulmonary embolism.

• Increased cholesterol levels: Danogen may alter lipid profiles, so regular monitoring of cholesterol is advised.

• Menstrual irregularities: May cause amenorrhea (absence of periods) or other menstrual cycle changes.

If any serious side effects occur, seek medical attention immediately.

Precautions:

• Pregnancy and Breastfeeding: Danogen should not be used during pregnancy as it can harm the fetus. It is also not recommended during breastfeeding as it can pass into breast milk.

• Liver Problems: Danogen can cause liver damage. People with a history of liver disease should avoid using this medication.

• Blood Clots: If you have a history of blood clotting disorders, inform your healthcare provider, as Danogen may increase the risk of clotting.

• Hormonal Conditions: Those with a history of breast cancer, uterine cancer, or ovarian cancer should avoid Danogen due to its hormonal effects.

Drug Interactions:

Danogen can interact with several medications, including:

• Anticoagulants (blood thinners) like warfarin, as Danogen may affect their action.

• Steroids or other hormonal treatments, as they may interact with Danogen’s hormonal activity.

• Liver enzyme inducers (such as phenytoin and carbamazepine), which may affect Danogen’s effectiveness.

Always inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and supplements.

Storage Instructions:

• Store at room temperature (15°C to 30°C).

• Keep in a cool, dry place away from moisture and direct sunlight.

• Keep out of reach of children.

  Disclaimer:

This product description is provided as general information and may not apply to all individuals. Always consult your healthcare provider for specific guidance and recommendations tailored to your health condition. If you experience any unusual or severe side effects, contact your doctor immediately.