Doxinate Tablet

Doxinate Tablet – Product Description

Brand Name: Doxinate
Active Ingredient: Doxylamine and Pyridoxine (Vitamin B6)
Formulation: Tablet
Manufacturer: M S Labo or Alkem Laboratories (varies by region)
Packging : strips of 30 dispersible tablets per pack.

Description:

Doxinate Tablet is a combination of two active ingredients: Doxylamine (an antihistamine) and Pyridoxine (Vitamin B6). It is commonly prescribed to prevent and treat nausea and vomiting associated with pregnancy (morning sickness), particularly in the first trimester. It works by alleviating nausea, vomiting, and morning sickness, making it easier for expectant mothers to maintain proper nutrition and hydration during early pregnancy.

Doxylamine is an antihistamine that works by blocking certain signals in the brain that cause nausea and vomiting. Pyridoxine helps support the proper function of the nervous system and aids in the management of nausea.

Indications:

• Morning Sickness: Doxinate is most commonly used for treating nausea and vomiting during pregnancy, often referred to as morning sickness, which can occur in the early stages of pregnancy.

• Hyperemesis Gravidarum: In more severe cases of pregnancy-related nausea and vomiting, known as hyperemesis gravidarum, Doxinate may be used alongside other treatments.

• Other Uses: In some cases, Doxinate may be prescribed off-label for nausea and vomiting associated with other conditions (e.g., motion sickness), but this is less common.

Dosage and Administration:

• Morning Sickness:

  • Initial dose: Typically, one tablet of Doxinate is taken at night before sleep.

  • Subsequent dose: Depending on the severity of symptoms, one tablet may be taken in the morning or additional doses may be taken as prescribed by your doctor.

  • Maximum dose: The typical daily dose is 2 to 4 tablets, depending on the response and the doctor’s recommendations.

Note: Always follow the prescribed dosage and instructions given by your healthcare provider. Do not take more than the recommended dose.

Side Effects:

Some common side effects of Doxinate may include:

• Drowsiness or sedation (due to the doxylamine component)

• Dry mouth

• Headache

• Dizziness

• Fatigue

• Constipation

Serious side effects are rare, but if any of the following occur, seek medical attention immediately:

• Severe allergic reactions (rash, itching, swelling, difficulty breathing)

• Confusion or mood changes

• Blurred vision

If you experience persistent or bothersome side effects, consult your healthcare provider.

Precautions:

• Pregnancy: Doxinate is specifically used to treat nausea and vomiting in pregnancy, especially during the first trimester. It is important to follow the prescribed dosage to avoid overdosing or complications.

• Lactation: Since doxylamine can pass into breast milk, it is advisable to consult your doctor before using it while breastfeeding.

• Medical History: Inform your doctor if you have a history of allergies to medications, particularly antihistamines like doxylamine. Additionally, inform them if you have liver, kidney, or heart issues.

• Sedation: Doxinate can cause drowsiness, so you should avoid activities that require full attention (e.g., driving) until you understand how the medication affects you.

• Drug Interactions: Inform your healthcare provider about any other medications you are taking, especially those for allergies, motion sickness, or sleep disorders, as there may be potential drug interactions.

Storage Instructions:

• Store at room temperature (15°C to 25°C).

• Keep away from moisture and direct sunlight.

• Keep out of reach of children.

Disclaimer:

Always use Doxinate as prescribed by your healthcare provider. If you have any concerns about your symptoms or the medication’s effects, consult your doctor. Do not hesitate to report any side effects to your healthcare professional.