Combigan Eye Drop (5ml)

Combigan Eye Drop (5ml) – Product Description

Brand Name: Combigan Eye Drop
Active Ingredients:

• Brimonidine Tartrate 0.2% w/v

• Timolol Maleate 0.5% w/v
  Drug Class: Combination of Alpha-2 Adrenergic Agonist and Beta-Adrenergic Blocker
  Manufactured By: Allergan
  Packaging Details: 5ml sterile eye drop bottle

Description:

Combigan Eye Drop is a prescription medication used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It combines two active ingredients:

• Brimonidine Tartrate: An alpha-2 adrenergic receptor agonist that decreases aqueous humor production and increases uveoscleral outflow, thereby lowering eye pressure.

• Timolol Maleate: A non-selective beta-adrenergic receptor blocker that reduces aqueous humor production, contributing to decreased IOP.

This dual-action formulation effectively lowers eye pressure, reducing the risk of optic nerve damage and vision loss associated with glaucoma.

Uses:

• Management of Elevated Intraocular Pressure: Effective in lowering high eye pressure in conditions like open-angle glaucoma and ocular hypertension when monotherapy is insufficient.

Dosage & Administration:

• Recommended Dose: Instill one drop into the affected eye(s) twice daily, approximately 12 hours apart.

• Administration Guidelines:

  • Wash hands thoroughly before use.

  • Tilt head back, pull down the lower eyelid to create a pouch, and instill one drop into the conjunctival sac.

  • Avoid touching the dropper tip to any surface to prevent contamination.

  • If using other ophthalmic medications, administer them at least 5 minutes apart.

Side Effects:

Common side effects may include:

• Eye redness, itching, or irritation

• Burning or stinging sensation upon instillation

• Blurred vision

• Dry mouth

• Drowsiness or fatigue

Serious side effects are rare but may include:

• Severe allergic reactions (e.g., swelling, difficulty breathing)

• Slow or irregular heartbeat

• Eye pain or swelling

If any severe reactions occur, discontinue use and seek medical attention immediately.

Precautions & Warnings:

• Contraindications:

  • Patients with bronchial asthma, severe chronic obstructive pulmonary disease (COPD), sinus bradycardia, heart block, or cardiac failure should not use this medication.

  • Not recommended for individuals with a known hypersensitivity to any component of the product.

• General Precautions:

  • Contact Lens Wearers: Remove contact lenses before instillation and wait at least 15 minutes before reinserting them.

  • Operating Machinery: May cause temporary blurred vision or drowsiness; avoid driving or operating machinery until vision is clear.

  • Systemic Absorption: Although applied topically, the medication can be absorbed systemically. Use with caution in patients with cardiovascular diseases, depression, or other conditions affected by beta-blockers or alpha agonists.

• Pregnancy & Lactation: Consult a healthcare provider before use if pregnant or breastfeeding, as the effects on fetal development and nursing infants are not well-established.

Storage Instructions:

• Store at room temperature (15°C to 25°C), protected from light and moisture.

• Keep the bottle tightly closed when not in use.

• Keep out of reach of children.

Disclaimer:

This information is provided for educational purposes only and should not replace professional medical advice. Always consult a healthcare provider before starting any new medication, including Combigan Eye Drops.